EUGENE -- The Oregon Ducks, a No. 5 national seed for the NCAA baseball tournament, host Cal State Fullerton, Austin Peay and Indiana State at PK Park in the Eugene Regional starting Friday.
It is the first national seeding in program history.
The Ducks finished 42-17 this season and 19-11 in the Pac-12 Conference. They were third in the league after a three-game sweep by the Oregon State to end the regular season.
Oregon opens the double-elimination tournament with Austin Peay (38-22), coming off its second consecutive Ohio Valley Conference tournament title.
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The Governors are making their second consecutive and fifth overall appearance in the NCAA tournament. Eugene is the farthest west the team has ever traveled. They have never before faced Oregon in baseball.
The regional opener will be followed by Fullerton (35-19) against Indiana State (41-17).
The Sycamores, an at-large bid out of the Missouri Valley Conference, have not been to the tournament since 1995. It is their eighth all-time appearance in the postseason.
Fullerton, the Big West Conference champion, is making its 21st straight postseason appearance. The Titans have won four College World Series titles.
Their latest national championship in 2004 came under current Oregon coach George Horton, who spent 11 seasons as head coach at Cal State Fullerton before taking over the Ducks' restored program in 2008.
Horton has been to the College World Series six times.
The winner in Eugene will face the winner of the Gary (Ind.) Regional, hosted by Purdue, in a Super Regional. The College World Series starts on June 15 at TD Ameritrade Park in Omaha, Neb.
Oregon hasn't hosted an NCAA baseball tournament game since 1954, but the school didn't field a team from 1982 to 2009. The Ducks also went to the postseason tournament in 1964 and 2010.
Oregon State is headed to the Baton Rouge Regional where they'll face Belmont on Friday.
It will be Oregon State's fourth straight trip to the NCAA tournament, a school record. The Beavers won back-to-back College World Series titles in 2006 and 2007.