Here is the schedule for Week 5 in the 2011 Mid-Columbia high school football season:
Thursday, Sept. 29
| CBBN 3A | ||
| Sunnyside | 7 | |
| Kennewick (Lampson Stadium) | 20 | F |
Friday, Sept. 30
| CBBN 4A | ||
| Chiawana | 22 | |
| Richland (Fran Rish Stadium) | 14 | F |
| Davis | 41 | |
| Walla Walla | 16 | F |
| Wentachee | 22 | |
| Eisenhower | 34 | F |
| Nonleague | ||
| Hermiston | 28 | |
| Moses Lake | 24 | F |
| CBBN 3A | ||
| Eastmont | 21 | |
| Pasco (Edgar Brown Stadium) | 16 | F |
| Hanford | 10 | |
| Southridge (Lampson Stadium) | 31 | F |
| Kamiakin | 28 | |
| West Valley | 23 | F |
| CWAC | ||
| East Valley | 6 | |
| Othello | 42 | F |
| Ellensburg | 28 | |
| Prosser | 32 | F |
| Ephrata | 33 | |
| Wapato | 13 | F |
| Grandview | 8 | |
| Quincy | 54 | F |
| Toppenish | 7 | |
| Selah | 24 | F |
| SCAC | ||
| Wahluke | 12 | |
| Royal | 57 | F |
| Columbia-Burbank | 7 | |
| Connell | 55 | F |
| Mabton | 0 | |
| River View | 46 | F |
| Nonleague | ||
| Naches Valley | 6 | |
| Kiona-Benton | 41 | F |
| Southeast 2B | ||
| Tri-Cities Prep | 0 | |
| Dayton | 30 | F |
| Waitsburg-Prescott | 33 | |
| DeSales | 14 | F |
| Southeast 1B | ||
| LaCrosse-Washtuchna | 40 | |
| Colton | 52 | F |
| Liberty Christian | 54 | |
| Garfield-Palouse | 46 | F |
| Sunnyside Christian | 14 | |
| Pomeroy | 40 | F |
| Touchet | 40 | |
| St. John-Endicott | 0 | F |
| Oregon | ||
| Hermiston | 28 | |
| Moses Lake | 24 | F |
| Stanfield | 55 | |
| Irrigon | 36 | F |
| Condon/Wheeler | 24 | |
| Echo | 36 | F |
| McLoughlin Union | 0 | |
| Umatilla | 24 | F |
